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Condition

Hypoglossal Nerve Diseases

Neurology

Overview

Diseases of the twelfth cranial (hypoglossal) nerve or nuclei. The nuclei and fascicles of the nerve are located in the medulla, and the nerve exits the skull via the hypoglossal foramen and innervates the muscles of the tongue. Lower brain stem diseases, including ischemia and MOTOR NEURON DISEASES may affect the nuclei or nerve fascicles. The nerve may also be injured by diseases of the posterior fossa or skull base. Clinical manifestations include unilateral weakness of tongue musculature and lingual dysarthria, with deviation of the tongue towards the side of weakness upon attempted protrusion.

This information is general and should not be treated as medical advice. Always speak directly with a qualified healthcare professional before making decisions about treatment, diagnosis, procedures, medicines or care.

Quick facts about Hypoglossal Nerve Diseases

Topic type
Condition
Category
Neurology
MeSH classification
C10.292.525

Preparing for an appointment about Hypoglossal Nerve Diseases

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  • Write down your symptoms and when they started.
  • Bring details of any medicines, supplements or previous treatments.
  • Ask what tests or assessments may be needed.
  • Ask what treatment or management options may be suitable.
  • Ask when you should seek urgent medical help or follow-up care.

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Source: Medical Subject Headings (MeSH), produced by the U.S. National Library of Medicine. EuroCareFinder is not endorsed by the National Library of Medicine. MeSH version: 2026.