Condition
Leukoencephalopathy, Progressive Multifocal
Neurology
Overview
An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
This information is general and should not be treated as medical advice. Always speak directly with a qualified healthcare professional before making decisions about treatment, diagnosis, procedures, medicines or care.
Quick facts about Leukoencephalopathy, Progressive Multifocal
- Topic type
- Condition
- Category
- Neurology
- MeSH classification
- C01.207.245.340.500|C01.207.399.750.500|C01.925.182.525.500|C01.925.256.721.500|C01.925.839.550|C10.228.140.430.520.750.500|C10.228.140.695.750|C10.228.228.245.340.500|C10.228.228.399.750.500|C10.314.450|C10.586.250.520.750.500
Preparing for an appointment about Leukoencephalopathy, Progressive Multifocal
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- Write down your symptoms and when they started.
- Bring details of any medicines, supplements or previous treatments.
- Ask what tests or assessments may be needed.
- Ask what treatment or management options may be suitable.
- Ask when you should seek urgent medical help or follow-up care.
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Source: Medical Subject Headings (MeSH), produced by the U.S. National Library of Medicine. EuroCareFinder is not endorsed by the National Library of Medicine. MeSH version: 2026.