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Condition

Small Fiber Neuropathy

Neurology

Overview

Disorder of the peripheral nerves that primarily impair small nerve fibers. The affected small nerve fibers include myelinated A-delta fibers (see A FIBERS) and unmyelinated C FIBERS. Because these small fibers innervate skin and help control autonomic function, their neuropathy presents with neuropathic pain, reduced thermal and pain sensitivity, and autonomic dysfunction (e.g. abnormal sweating or facial flushing). Small fiber neuropathy can be idiopathic or associated with underlying diseases (e.g., AMYLOIDOSIS; DIABETES MELLITUS; SARCOIDOSIS; or VASCULITIS).

This information is general and should not be treated as medical advice. Always speak directly with a qualified healthcare professional before making decisions about treatment, diagnosis, procedures, medicines or care.

Quick facts about Small Fiber Neuropathy

Topic type
Condition
Category
Neurology
MeSH classification
C10.668.829.860

Preparing for an appointment about Small Fiber Neuropathy

If you are speaking with a healthcare professional about Small Fiber Neuropathy, it can help to prepare a few details in advance.

  • Write down your symptoms and when they started.
  • Bring details of any medicines, supplements or previous treatments.
  • Ask what tests or assessments may be needed.
  • Ask what treatment or management options may be suitable.
  • Ask when you should seek urgent medical help or follow-up care.

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Source: Medical Subject Headings (MeSH), produced by the U.S. National Library of Medicine. EuroCareFinder is not endorsed by the National Library of Medicine. MeSH version: 2026.