Wolfram Syndrome

Overview

A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.

This information is general and should not be treated as medical advice. Always speak directly with a qualified healthcare professional before making decisions about treatment, diagnosis, procedures, medicines or care.

Quick facts about Wolfram Syndrome

Topic type

Condition

Category

Ophthalmology

MeSH classification

C09.218.458.341.186.500.750|C10.292.700.225.500.980|C10.574.500.662.980|C10.597.751.418.341.186.500.750|C10.597.751.941.162.625.750|C11.270.564.980|C11.640.451.451.980|C11.966.075.375.750|C12.050.351.968.419.135.875|C12.200.777.419.135.875|C12.950.419.135.875|C16.131.077.299.750|C16.320.290.564.980|C16.320.400.630.980|C18.452.394.750.124.960|C19.246.267.960|C19.700.159.875

Preparing for an appointment about Wolfram Syndrome

If you are speaking with a healthcare professional about Wolfram Syndrome, it can help to prepare a few details in advance.

• Write down your symptoms and when they started.
• Bring details of any medicines, supplements or previous treatments.
• Ask what tests or assessments may be needed.
• Ask what treatment or management options may be suitable.
• Ask when you should seek urgent medical help or follow-up care.

Finding care related to Wolfram Syndrome

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